02:26
Sportsbet's Nathan Brown and Kane Cornes preview the game between the Lions and Eagles at the Gabba
Bailey Williams comes into the Eagles side alongside speedster Jack Petruccelle and high-flying forward Liam Ryan. Injured forward Jake Waterman is out, as is with utility Jack Hutchinson.
The Lions bring in former Sun Sam Day for his first game for the club and have named mid-season draftee Will McLachlan for his AFL debut, with ruck Darcy Fort has been omitted.
In the second match if the day, North Melbourne and Melbourne will both be out to avenge disappointing round one losses when they meet at Marvel Stadium on Sunday afternoon.
The Kangaroos missed an opportunity to start their season on the right foot in round one as it kept pace with the undermanned Western Bulldogs while not quite doing enough to get its nose in front.
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But the Roos can turn to promising signs in the defeat to the Dogs, as well as in the narrow loss when finishing strongly against the Demons last year, but at some stage will need to find wins to prove they are heading in the right direction.
Melbourne looked set to put yet another off-season of conjecture and controversy behind it with a win over the Giants last week before the top-four hopefuls booted the last two goals of the game to snatch victory.
The Demons did a lot right against the Giants but will have no time to lick their wounds ahead of a clash with a Kangaroos outfit that pushed them to the limit last year, if they want to avoid a dreaded 0-2 start.
Small forward Charlie Spargo will play his first match for the Demons since Opening Round last year, having recovered from a long-running Achilles issue. First-year player Harvey Langford makes way, while Aidan Johnson (suspension) and Caleb Windsor (foot) will also miss.
North Melbourne has brought in midfielder Dylan Stephens and tall Toby Pink for the clash.